Gene (or Strain) | Phenotype Description | Chromosome |
|---|---|---|
Lse | Low set ear; vascular hazy cornea, homozygotes have cataracts, AD | 7 |
nm1863 | Cataract, abnormal iris and cornea, AR | 12 |
wa3 | Waved 3, mice have wavy coat, eyelids fail to develop and have an enlarged heart and esophagus, AR | 12 |
eyeless | Strain with anophthalmos in 80% of offspring. Mice with intact globes have micro-ophthalmia and frequently congenital corneal perforations, with collapse of the anterior chamber, AR | 3 |
A/J | Crystal deposits in iris, XR | X |
Nm2557 | X-linked model for aniridia: heterozygous females have a small iris, homozygous females and males have a cataract, XD | X |
nm2619 | Mouse model for PHPV, AR | 9 |
Gene (or Strain) | Phenotype Description | Chromosome |
|---|---|---|
DBA/2J | Pigmentary glaucoma model, with essential iris atrophy with subsequent angle clogging with pigment. Mice develop bupthalmos and progressively enlarged optic cups. At least two recessive genes are involved [Chang, 1999] | |
gene #1 ipd iris pigment dispersion, AR | 6 | |
gene #2 isa iris stromal atrophy, AR | 4 | |
nm2702 | swollen eyes, inner retina loss, ON cupping , AR | 11 |
AD=autosomal dominant, AR=autosomal recessive, XD=X-linked Dominant, XR=X-linked recessive |